Release Notes - Geneious (2024)

New feature highlights for Geneious Biologics include support for non-antibody therapeutic peptides and the ability to share your analysis options with your team.

• Analysis of non-antibody therapeutic peptides and proteins
• Easily accessible new Graphs tab
• Save and share analysis settings within your organization
• Better support for scFv/bi-specifics: Linker databases

Geneious Prime 2024.0 Feature Overview

Watch for an overview of the new features in Geneious Prime 2024.0

• Cloning Validation: New visual and semi-automated step to add, export and record validation metadata during batch plasmid validation.
• Map to Reference Algorithm Advisor: Interactive quiz to help you decide which algorithm is the best fit for you data.

Exciting new features for Geneious Biologics include manual sequence editing, dual nanobody (VHH-VHH) support, and protein scaffold reference databases.

• Manual Sequence Editing
• NGS Antibody Annotator
• Enrichment and Alignment Visualizations
• VHH and Dual Nanobody Analysis
• Reference Database Creator

Geneious Prime 2023.2 Feature Overview

Watch for an overview of the new features in Geneious Prime 2023.2

• De Novo Assembly Algorithm Advisor: Interactive quiz to help you decide which algorithm is the best fit for your data.
• Cloud Personal Workspace: Access your data from multiple computers with secure personal data storage in Geneious Prime.
• Export Lengths Graph Data: Quickly and easily export a csv file with your sequence length distribution data.
• Improvements to STAR RNA-seq aligner: You can now use the STAR RNA-seq aligner in Geneious with multiple references.

Exciting new features for Geneious Biologics include:

• An improved user interface experience
• Positional Liabilities based on antibody numbering schemes
• Adding labels to a selection of sequences
• Clustering options now available in Single Clone Antibody Analysis
• New speedier integration with Geneious Prime

New Features in Geneious Prime 2023.1

• Dotmatics Platform Integration plugin: Launch the registration workflow to register your sequences in Dotmatics Bioregister.
• Import .sbd files: Geneious Prime can now import DNAStar Lasergene SeqBuilder(Pro) .sbd file format.
• Geneious Cloud Database: Access your data from multiple computers with secure personal data storage in Geneious Prime.

New features for Geneious Biologics include:

• More Numbering Schemes for annotation
• Streamlined Extract/Export Features
• Import Sequences from .csv and excel files

Geneious Prime 2023.0 Feature Overview

Watch for an overview of the new features in Geneious Prime 2023.0

• Primer Specificity Testing: Design target-specific primers in one step with new primer specificity testing.
• Cloning Validation: New visual tool for automating sequence alignment during batch plasmid validation
• STAR RNA-seq mapper: Added STAR, a RNA-seq mapper that performs highly accurate spliced sequence alignment.
• CRISPR Improvements: Added more PAMs and the ability to select individual sequences for specificity testing.

What's New in Geneious Prime 2022.2?

• In-Fusion cloning: Perform low or high throughput In-Fusion Cloning with pre-optimized settings.
• Parts Cloning Support for Proteins: Scale up your construct engineering with combinatorial assembly of proteins.
• Primer Extension Detection: Automatically detect and annotate extensions on your primer databases during import.

New features and functionality for Geneious Biologics includes:

• Customizable clustering options for Antibody Annotator
• History Viewer tab to track input data and more across documents
• Copy-paste sequences for Quick Analysis
• Chain Combinations tables in Single Clone Antibody Analysis

What's New in Geneious Prime 2022.1?

• Batch Golden Gate: Perform Golden Gate cloning in batch using sequence lists and stop doing your Golden Gate cloning operations one by one.
• Parts Cloning: Scale up your cloning throughput with added support for Parts Cloning, combining every possible combination from your lists of parts.
• Primer Import: Easily import and characterize primer databases stored in excel spreadsheets so you can take full advantage of the primer tool suite, including Test with Saved Primers.

What's New in Geneious Prime 2022?

• Annotate by BLAST - Automatically annotate your ORFs, CDS and mRNA regions using BLAST.
• Command Line Interface - Run Geneious Prime operations and workflows as part of your broader bioinformatic pipelines locally or execute on more powerful servers.
• Dark Mode - Comfortably analyze your data at any time of the day or night with Geneious Prime in dark mode
• Experimental Features - Try out features we are experimenting with and let us know your thoughts
• Apply Optimized Codon - Easily add and remove optimized codons to your sequence
• Manage Document Table Columns - Quickly organize your data with multiple column selection
• Highlight Mismatching Bases - Highlight mismatching base calls in your chromatograms

What's New in Geneious Prime 2021.2?

• Virtual gel improvements: Easily view multiple sequences with the display of restriction enzymes in lane headings, and quick access to an exportable list of fragments
• View CRISPR cut sites: Easily view and compare CRISPR cut sites between your guide RNAs
• View invalid CDS annotations: Improve your cloning workflows by quickly determining CDS annotations with premature stop codons
• Batch edit annotations: Quickly add or edit annotations in batch by copying properties from other annotations, sequences or documents

In Q2 2021 we have focused on improving visualizations and overall usability in Geneious Biologics. Highlights include Graph Usability Improvements, Moveable Folders, and REST API.

What's New in Geneious Prime 2021.1?

• New filter interface: Locate documents quickly in any table with the new filter button added to the status bar.
• Adjustable sequence selection: Adjust either end of the selected region in the Sequence View by dragging.
• Amino acid numbering: Live numbering can now be shown alongside the translated amino acids on nucleotide sequences.

What's New in Geneious Prime 2021?

• Geneious Prime gets a new look: Enjoy the new look and feel of Geneious Prime with an updated design, including new icons and font.
• Highlighted methylation sites for restriction enzymes: Quickly visualize restriction sites affected by Dam, Dcm and Eco*kI methylation.
• Accessible sequence viewer statistics: Easily sort and export your protein and nucleotide statistics within the document table.
• New CRISPR on-target scoring method: Confidently design your guide RNAs using the Doench et al. 2016 CRISPR on-target scoring algorithm.

Geneious Prime 2020 brings exciting new functionality to transform raw sequence data into meaningful visualizations.

• Analyze CRISPR Editing Results
• Enhanced Search Options
• Codon Optimization Improvements